Promoter hypermethylation of FANCF plays an important role in the occurrence of ovarian cancer through disrupting fanconi anemia-BRCA pathway - Concepedia

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Promoter hypermethylation of FANCF plays an important role in the occurrence of ovarian cancer through disrupting fanconi anemia-BRCA pathway

DOI Full Paper Access

69

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0

References

2006

Year

Zehua Wang, Min Li, Shi Lu, Yuan Zhang, Hongbo Wang

Cancer Biology & Therapy

Abstract

The results showed that FANCF methylation regulates the expression of FANCF at both mRNA and protein levels. Methylation-induced inactivation of FANCF plays an important role in the occurrence of ovarian cancers via disrupting the FA-BRCA pathway.