Prevalence of magnetic resonance imaging–defined atrophic and hypertrophic phenotypes of knee osteoarthritis in a population‐based cohort

Abstract

The majority of knees with severe tibiofemoral cartilage damage exhibited moderate to large osteophytes. The larger the osteophyte, the more likely was the presence of severe cartilage damage. A minority of knees exhibited the atrophic phenotype, which also included knees without radiographic OA. The hypertrophic phenotype was extremely rare.