Capecitabine induced vasospastic angina

Oral capecitabine as an alternative to i.v. 5-fluorouracil-based adjuvant therapy for colon cancer: safety results of a randomized, phase III trial

Werner Scheithauer, J McKendrick, S. Begbie et al. · Annals of Oncology · 2003 · 275 citations · Full text

Medicine, Oncology, Pharmacology +17

In vitro evidence that myocardial ischemia resulting from 5-fluorouracil chemotherapy is due to protein kinase C-mediated vasoconstriction of vascular smooth muscle.

Morris Mosseri, Howard Fingert, Lyuba Varticovski et al. · PubMed · 1993 · 198 citations

Medicine, Cardiology, Pharmacology +17

5-Fluorouracil induces arterial vasocontractions

T Südhoff, M. Enderle, Michaela Pahlke et al. · Annals of Oncology · 2004 · 165 citations

Medicine, Pharmacology, Pharmacotherapy +10

Cardiotoxicity of 5-fluorouracil in 1350 patients with no prior history of heart disease.

Panayota Tsibiribi, Jacques Descotes, Catherine Lombard‐Bohas et al. · PubMed · 2006 · 64 citations

Medicine, Cardiology, Pharmacology +14