Antimicrobial Agents and Chemotherapy · 2014 · 18 citations · 3 references
PharmacyPharmacologyPharmacotherapyAntimicrobial PharmacologyAntimicrobial PharmacotherapyHepatologyCholestatic Liver InjuryHepatic ImpairmentHepatotoxicity ManagementHepatotoxicity MechanismsLiver DiseaseAntimicrobial HepatotoxicityDrug-induced Hepatic NecrosisDrug-induced Liver Injury AssessmentHepatocellular Liver InjuryInflammatory Liver InjuryLiver Function Test PanelsLiver Toxicity AssessmentMatched Cohort Analysis
A patient receiving daptomycin developed asymptomatic transaminitis and hyperbilirubinemia without concurrent multiorgan dysfunction or elevation of his creatinine kinase level. After ruling out other etiologies, the liver injury was attributed to daptomycin and was subsequently resolved. A single-center retrospective cohort analysis of baseline and follow-up liver function panels (n = 614) from all admissions from 2008 to 2013 during which daptomycin was administered did not reveal any other cases of probable or definite drug-induced liver injury associated with daptomycin.
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A method for estimating the probability of adverse drug reactions
C. A. Naranjo, U. Busto, Edward M. Sellers et al. · Clinical Pharmacology & Therapeutics · 1981 · 11.6K citations