Advanced Materials · 2012 · 2K citations · 29 references
Natural SciencesMaterials ScienceOncologyBiomaterialsBiophotonicsNanomaterialsCancer NanomedicineNanocarriers For TherapeuticsNanomedicineNanoparticle DesignPhotothermal TherapyTheranostic NanoparticlesBiodegradable Photothermal AgentsBiomaterial BiocompatibilityCancer NanotherapyCancer Photothermal TherapyNanomaterials For Photothermal TherapyPhotothermal Ablation Of TumorsPhotothermal EffectsPower Density
A new generation of photothermal therapeutic agents based on biopolymer dopamine-melanin colloidal nanospheres is described. Benefitting from their naturally wide distribution in humans, dopamine-melanin colloidal nanospheres exhibit robust biocompatibility and biodegradability, and provide up to 40% photothermal conversion efficiency. After administration, they can efficiently damage tumors at low power density and short irradiation time without damaging healthy tissues.
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Graphene in Mice: Ultrahigh In Vivo Tumor Uptake and Efficient Photothermal Therapy
Kai Yang, Shuai Zhang, Guoxin Zhang et al. · Nano Letters · 2010 · 2.4K citations