Disc Inflammation Potentially Promotes Axonal Regeneration of Dorsal Root Ganglion Neurons Innervating Lumbar Intervertebral Disc in Rats

Abstract

The present results suggest that disc inflammation potentially promotes axonal growth of DRG neurons innervating the disc. In light of the strong correlation between the expression of calcitonin gene-related peptide and nerve growth factor receptor, it is most likely that nerve growth factor-sensitive DRG neurons extend their axons following disc inflammation.