Reproducibility of Dynamic Contrast-enhanced MR Imaging. Part I. Perfusion Characteristics in the Female Pelvis by Using Multiple Computer-aided Diagnosis Perfusion Analysis Solutions

Abstract

A considerable variability for DCE MR imaging pharmacokinetic parameters (K(trans), k(ep), v(e), iAUGC) was found among commercially available perfusion analysis solutions. Therefore, clinical comparability across perfusion analysis solutions is currently not warranted. Agreement on a postprocessing standard is paramount prior to establishing DCE MR imaging as a widely incorporated biomarker.