Sexually Transmitted Diseases · 1977 · 61 citations · 0 references
MedicineInfectious DiseasesMaternal HealthMaternal-fetal MedicinePediatric EpidemiologyPediatric Infectious DiseasesCongenital InfectionsInfant Infectious DiseasesPerinatal InfectionCongenital Syphilis PreventionInadequate Prenatal CareMaternal SyphilisSyphilis Diagnosis In PregnancySyphilis DiagnosticsSyphilis EpidemiologySystematic Literature ReviewTherapeutic Decision-making
A retrospective questionnaire survey of a sample of 173 of the 360 cases of early congenital syphilis reported in 1972 revealed serious problems with diagnostic certainty, prevention, and treatment of congenital syphilis. Only 24 (13.9%) of the reported cases could be categorized as probably or definite cases based on criteria developed from a literature review. Forty percent of the mothers received no prenatal care and an additional 19% received no prenatal care until the third trimester. Initial and followup serologic testing was inadequate in those who received care. Eighty-three different penicillin treatment schedules were used in the treatment of 128 infants. Carefully reasoned diagnostic and therapeutic decision making about the management of congenital syphilis appears to be lacking.