Activation of Akt/GSK-3β signaling pathway is involved in intermedin1–53 protection against myocardial apoptosis induced by ischemia/reperfusion

A Unified Model for Apical Caspase Activation

Kelly M. Boatright, Martin Renatus, Fiona L. Scott et al. · Molecular Cell · 2003 · 941 citations · Full text

Signal Transduction, Molecular Physiology, Signaling Pathway +10

Akt Promotes Survival of Cardiomyocytes In Vitro and Protects Against Ischemia-Reperfusion Injury in Mouse Heart

Yasushi Fujio, Thao Nguyen, Detlef Wencker et al. · Circulation · 2000 · 839 citations · Full text

Requirement for Caspase-2 in Stress-Induced Apoptosis Before Mitochondrial Permeabilization

Patrice Lassus, Ximena Opitz-Araya, Yuri Lazebnik · Science · 2002 · 716 citations

Inflammation, Signal Transduction, Mitochondrial Function +12

Myocardial Protection by Insulin at Reperfusion Requires Early Administration and Is Mediated via Akt and p70s6 Kinase Cell-Survival Signaling

Anne K. Jonassen, Michael N. Sack, Ole D. Μjøs et al. · Circulation Research · 2001 · 517 citations · Full text

Intermedin Is a Calcitonin/Calcitonin Gene-related Peptide Family Peptide Acting through the Calcitonin Receptor-like Receptor/Receptor Activity-modifying Protein Receptor Complexes

Jaesook Roh, Chia Lin Chang, Alka Bhalla et al. · Journal of Biological Chemistry · 2004 · 442 citations · Full text