Concepedia

p62/SQSTM1 is overexpressed and prominently accumulated in inclusions of sporadic inclusion-body myositis muscle fibers, and can help differentiating it from polymyositis and dermatomyositis

Anna Nogalska, Chiara Terracciano, Carla D’Agostino, W. King Engel, Valerie Askanas

Acta Neuropathologica · 2009 · 142 citations · 32 references

DOI

Concepts

References

32

p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy

Serhiy Pankiv, Terje Høyvarde Clausen, Trond Lamark et al. · Journal of Biological Chemistry · 2007 · 4.5K citations · Full text

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

Geir Bjørkøy, Trond Lamark, Andreas Brech et al. · The Journal of Cell Biology · 2005 · 3.2K citations · Full text

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

S Ohkuma, Brian D. Poole · Proceedings of the National Academy of Sciences · 1978 · 2.2K citations · Full text

, , +19

Epoxomicin, a potent and selective proteasome inhibitor, exhibits<i>in vivo</i>antiinflammatory activity

Lihao Meng, Royce Mohan, Benjamin H. Kwok et al. · Proceedings of the National Academy of Sciences · 1999 · 927 citations

Sequestosome 1/p62 Is a Polyubiquitin Chain Binding Protein Involved in Ubiquitin Proteasome Degradation

M. Lamar Seibenhener, Jeganathan Ramesh Babu, Thangiah Geetha et al. · Molecular and Cellular Biology · 2004 · 697 citations · Full text

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