Selective Synthesis of Fused 1,4‐ and 1,2‐Dihydropyridines by Domino Reactions of Arylamines, Acetylenedicarboxylate, Aldehydes, and Cyclic 1,3‐Diketones

Abstract

Abstract A practical procedure for the preparation of fused 1,4‐dihydropyridines was developed through the domino four‐component reactions of arylamines, acetylenedicarboxylate, aromatic aldehydes, and cyclic 1,3‐diketones in acetic acid. Unusual fused 1,2‐dihydropyridines can also be efficiently prepared by controlling the reaction conditions.