<scp>AMPA</scp> receptor subunits expression and phosphorylation in cingulate cortex in rats following esophageal acid exposure

Abstract

The underlying mechanism of acid-induced cortical sensitization involves upregulation and CaMKII-mediated phosphorylation of GluA1. These molecular changes of AMPA receptors subunit GluA1 in the cortical neurons might play an important role in acid-induced esophageal hypersensitivity.