Straightforward Synthesis of Bridged Azaoxa Skeletons: Gold‐Catalyzed Aminoketalization of Garner’s Aldehyde‐Derived Alkynes

Abstract

Building bridges with gold: Bridged azaoxa skeletons have been efficiently prepared from easily accessible alkynyloxazolidine substrates under mild reaction conditions (see scheme; Boc=tert-butoxycarbonyl). The reactions were found to proceed with complete control of the regio- and stereoselectivity of the products in the presence of a combined gold/silver and acid catalyst system. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.