Concepedia

Homocysteine Levels in Patients with Heart Failure with Preserved Ejection Fraction

Ertuğrul Okuyan, Ahmet Uslu, Mehmet Akif Çakar, İrfan Şahin, İmran Önür, Asım Enhoş, Halil İbrahim Biter, Şükrü Çetin, Mustafa Hakan Dinçkal

Cardiology · 2010 · 27 citations · 17 references

DOI

Abstract

Our results suggest that hyperhomocysteinemia is prevalent in heart failure with preserved ejection fraction. Larger scale studies are needed to clarify its pathogenic mechanisms and effects on the natural history of heart failure.

References

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Diastolic Heart Failure — Abnormalities in Active Relaxation and Passive Stiffness of the Left Ventricle

Michael R. Zile, Catalin F. Baicu, William H. Gaasch · New England Journal of Medicine · 2004 · 1.5K citations · Full text

Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen.

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Diastolic Dysfunction in Normotensive Men with Well-Controlled Type 2 Diabetes

Paul Poirier, Peter Bogaty, Caroline Garneau et al. · Diabetes Care · 2001 · 617 citations · Full text