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Synthesis and discovery of novel piperidone-grafted mono- and bis-spirooxindole-hexahydropyrrolizines as potent cholinesterase inhibitors

Yalda Kia, Hasnah Osman, Raju Suresh Kumar, Vikneswaran Murugaiyah, Alireza Basiri, Subbu Perumal, Habibah A. Wahab, Choi Sy Bing

Bioorganic & Medicinal Chemistry · 2013 · 103 citations · 22 references

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22

The Protein Data Bank

Helen M. Berman · Nucleic Acids Research · 2000 · 39.8K citations

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Atomic Structure of Acetylcholinesterase from <i>Torpedo californica</i> : A Prototypic Acetylcholine-Binding Protein

Joel L. Sussman, Michal Harel, Felix Frolow et al. · Science · 1991 · 2.7K citations

, , +17

Asymmetric Multicomponent Reactions (AMCRs): The New Frontier

Diego J. Ramón, Miguel Yus · Angewandte Chemie International Edition · 2005 · 1.7K citations

, , +8

Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase.

Michal Harel, Isabelle J. Schalk, Laurence Ehret‐Sabatier et al. · Proceedings of the National Academy of Sciences · 1993 · 903 citations

, , +16

Crystal Structure of Human Butyrylcholinesterase and of Its Complexes with Substrate and Products

Yvain Nicolet, Oksana Lockridge, Patrick Masson et al. · Journal of Biological Chemistry · 2003 · 830 citations · Full text

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