T-Lymphocyte Subpopulations in Homosexual Men

Abstract

IN the past two years there has been an unprecedented outbreak of Kaposi's sarcoma, Pneumocystis carinii pneumonia, and other opportunistic infections in male homosexuals and, to a lesser extent, in drug addicts in the United States.1 , 2 These cases have been concentrated in New York City and California, and as of January 13, 1982, 216 cases had been reported to the Centers for Disease Control.3 Nineteen cases with immunologic evaluation were reported in December 1981.4 5 6 All patients had evidence of cellular immunodeficiency with cutaneous anergy, reduced numbers of T lymphocytes, and impaired lymphocyte transformation. Four patients described by Gottlieb et al. . . .