<i>E‐cadherin</i> expression in early gastric carcinoma and correlation with lymph node metastasis

Abstract

Our results suggest that methylation of E-cadherin is a frequent, early event in gastric carcinoma progression, and is correlated significantly with downregulated E-cadherin expression. Inactivation of E-cadherin might be involved in metastasis in EGC and play an important role in microscopic differentiation.