Concepedia

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

Yoshiya Kawaguchi, Bonnie Cooper, Maureen Gannon, Michael Ray, Raymond J. MacDonald, Christopher V.E. Wright

Nature Genetics · 2002 · 1K citations · 21 references

DOI

Concepts

References

21

Insulin-promoter-factor 1 is required for pancreas development in mice

Jörgen Jönsson, Lena Carlsson, Helena Edlund · Nature · 1994 · 1.8K citations

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PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

Martin F. Offield, Tom L. Jetton, Patricia A. Labosky et al. · Development · 1996 · 1.5K citations

, , +16

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

Guoqiang Gu, Jolanta Dubauskaite, Douglas A. Melton · Development · 2002 · 1.5K citations

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Differentiation of Embryonic Stem Cells to Insulin-Secreting Structures Similar to Pancreatic Islets

Nadya Lumelsky, Olivier Blondel, Pascal Laeng et al. · Science · 2001 · 1.5K citations

, , +17

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage.

Merja Lakso, José G. Pichel, James Gorman et al. · Proceedings of the National Academy of Sciences · 1996 · 1.1K citations · Full text

, , +15