Concepedia

Publication | Open Access

IL28B, HLA-C, and KIR Variants Additively Predict Response to Therapy in Chronic Hepatitis C Virus Infection in a European Cohort: A Cross-Sectional Study

DOIFull Paper Access

180

Citations

29

References

2011

Year

Vijayaprakash Suppiah, Silvana Gaudieri, Nicola J. Armstrong, Kate O'Connor, Thomas Berg, Martin Weltman, Maria Lorena Abate, Ulrich Spengler, Margaret F. Bassendine, Gregory J. Dore,
PLoS Medicine

Abstract

Genotyping for IL28B, HLA-C, and KIR genes improves prediction of HCV treatment response. These findings support a role for natural killer (NK) cell activation in PegIFN/R treatment-induced clearance, partially mediated by IL28B.

References

YearCitations

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