Role of Urinary Levels of Endothelin-1, Monocyte Chemotactic Peptide-1, and<i>N</i>-Acetyl Glucosaminidase in Predicting the Severity of Obstruction in Hydronephrotic Neonates

Abstract

The urinary MCP-1/Cr ratio is significantly elevated in neonates with severe obstruction requiring surgical intervention. Based upon these results, urinary MCP-1/Cr may be useful in identification of severe obstructive hydronephrosis in neonates.