Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

George A. Calin, Cinzia Sevignani, Calin Dan Dumitru et al. · Proceedings of the National Academy of Sciences · 2004 · 4.1K citations · Full text

Life Sciences, Genetics, Oncology +13

Modulation of microRNA processing by p53

Hiroshi Suzuki, Kaoru Yamagata, Koichi Sugimoto et al. · Nature · 2009 · 1.1K citations

Life Sciences, Genetics, Molecular Biology +12

p53 represses c-Myc through induction of the tumor suppressor <i>miR-145</i>

Mohit Sachdeva, Shoumin Zhu, Fangting Wu et al. · Proceedings of the National Academy of Sciences · 2009 · 845 citations

Medicine, Cancer Biology, Oncology +15

Role of miR-143 targeting KRAS in colorectal tumorigenesis

Xiaoli Chen, Xu Guo, Hao Zhang et al. · Oncogene · 2009 · 550 citations

Medicine, Molecular Biology, Oncology +11

RETRACTED: Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development

Flavia Pichiorri, Sung-Suk Suh, Alberto Rocci et al. · Cancer Cell · 2010 · 443 citations · Full text

Medicine, Molecular Biology, Oncology +16