Retinoblastoma with 13q- Chromosomal Deletion Associated with Maternal Paracentric Inversion of 13q

Abstract

A girl with sporadic unilateral retinoblastoma and mental retardation has an interstitial deletion in the long arm of chromosome 13. Her mother has a paracentric inversion of one chromosome 13; the deleted chromosome 13 in the daughter is derived from the mother's normal chromosome 13.