Concepedia

1H-Imidazo[4,5-c]quinoline derivatives as novel potent TNF-α suppressors: synthesis and structure–activity relationship of 1-, 2-and 4-substituted 1H-imidazo[4,5-c]quinolines or 1H-imidazo[4,5-c]pyridines

Tomoyuki Izumi, Jun Sakaguchi, M. TAKESHITA, Harumi Tawara, Kenichi Kato, Hitomi Dose, Tomomi Tsujino, Yoshinari Watanabe, Hideo Kato

Bioorganic & Medicinal Chemistry · 2003 · 32 citations · 11 references

DOI

Concepts

References

11

An endotoxin-induced serum factor that causes necrosis of tumors.

E A Carswell, Lloyd J. Old, Robert Kassel et al. · Proceedings of the National Academy of Sciences · 1975 · 4.5K citations · Full text

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Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor ? monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis

Ravinder N. Maini, Ferdinand C. Breedveld, Joachim R. Kalden et al. · Arthritis & Rheumatism · 1998 · 1.6K citations

, , +17

Life‐threatening histoplasmosis complicating immunotherapy with tumor necrosis factor α antagonists infliximab and etanercept

Jong‐Hoon Lee, Nancy R. Slifman, Sharon K. Gershon et al. · Arthritis & Rheumatism · 2002 · 448 citations

, , +10

Enhancement of the innate and cellular immune response in patients with genital warts treated with topical imiquimod cream 5%

István Arany, Stephen K. Tyring, Margaret Stanley et al. · Antiviral Research · 1999 · 123 citations

, , +14

Structure−Activity Relationships of a Series of Pyrrolo[3,2-<i>d</i>]pyrimidine Derivatives and Related Compounds as Neuropeptide Y5 Receptor Antagonists

Mark H. Norman, Ning Chen, Zhidong Chen et al. · Journal of Medicinal Chemistry · 2000 · 84 citations · Full text

, , +17