Journal of Epidemiology · 2004 · 40 citations · 19 references
MedicineObstetricsPediatricsPediatric EndocrinologyPediatric EpidemiologyPerinatal EpidemiologyCongenital AnomaliesCongenital Disorder EpidemiologyHypospadias RepairAssessment Of Congenital AnomaliesBirth Prevalence EstimationCongenital Disorder IncidenceDiagnostic Criteria PrevalenceDistal Hypospadias RepairProximal Hypospadias RepairSurgical Repair Of Hypospadias
BACKGROUND: Hypospadias is one of the most common congenital anomalies in the world. Recently, increases in the prevalence of hypospadias have been reported in various countries including Japan. In this study, we examined whether the prevalence of hypospadias in Hokkaido, Japan, increased or not, using standardized diagnostic criteria. We also investigated the degree of its severity. METHODS: We calculated prevalence of hypospadias using hospital records of hypospadias repair in Hokkaido. The prevalence from 1985 through 1997 by dividing the number of patients obtained from hospital records by the number of births. RESULTS: The average prevalence of hypospadias in Hokkaido was 3.9 per 10,000 births, and did not significantly change (p=0.7). The average proportions of distal, proximal and chordee alone were 56.7%, 39.6% and 3.7%, respectively. The decrease in the proportion of the proximal type was statistically significant (p=0.05) for the entire time period, whereas the proportion of the distal type did not have a significant upward trend for the observed 13 years (p=0.1). CONCLUSION: No significant changes in the prevalence of hypospadias existed in Hokkaido.
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Hypospadias Trends in Two US Surveillance Systems
Leonard J. Paulozzi, J. David Erickson, Richard J. Jackson · PEDIATRICS · 1997 · 564 citations
Medicine, Pediatrics, Urology +7
Hypospadias in sons of women exposed to diethylstilbestrol in utero: a cohort study
Helen Klip, Janneke Verloop, Jan D. van Gool et al. · The Lancet · 2002 · 326 citations