Nosocomial bacterial infections in a tertiary hospital in Ethiopia

Abstract

The aim of this study was to determine the magnitude of nosocomial infection and isolate the bacterial aetiologic agents in a tertiary hospital. A total of 215 patients admitted to surgical wards and intensive care unit were followed prospectively. Specimens from patients were determined using standard techniques. Of the patients observed, 77 (35.8%) had 84 (39.1%) nosocomial infections. The overall incidence of nosocomial infections was 35.8/100 patients. Surgical site, urinary tract and blood stream infections comprised 38 (49.4%), 23 (29.8%) and 16 (20.8%), respectively. Of the bacterial isolates, 58/84 (69.0%) were Gram negative and 26/84 (31.0%) Gram positive. Pseudomonas aeruginosa (22.7%) and Escherichia coli (45.8%) were the major causes of surgical site and urinary tract infections, respectively. Staphylococcus aureus was isolated in 37.5% of the blood stream infections. The incidence of nosocomial infection in the hospital was high. There is a need to reduce the problem with continuous surveillance and the implementation of infection prevention strategies.