Simplex optimization of the response from chemical systems

Sequential Application of Simplex Designs in Optimisation and Evolutionary Operation

W. Spendley, G. R. Hext, F. R. Himsworth · Technometrics · 1962 · 1.3K citations

Public Health, Design, Design Optimization +6

Orthogonal Main-Effect Plans for Asymmetrical Factorial Experiments

Sidney Addelman · Technometrics · 1962 · 672 citations

Public Health, Biostatistics, Experimental Design +11

The Exploration and Exploitation of Response Surfaces: Some General Considerations and Examples

George E. P. Box · Biometrics · 1954 · 486 citations

Engineering, Systems Engineering, Surface Engineering +8

Symmetrical and Asymmetrical Fractional Factorial Plans

Sidney Addelman · Technometrics · 1962 · 197 citations

Public Health, Design, Experimental Design +7

The Exploration and Exploitation of Response Surfaces: An Example of the Link between the Fitted Surface and the Basic Mechanism of the System

George E. P. Box, P. V. Youle · Biometrics · 1955 · 182 citations

Natural Sciences, Chemical Engineering, Chemical Kinetics +12