Critical Care Medicine · 2004 · 102 citations · 17 references
Medications delivered by continuous infusion, particularly those that are weight based, can contribute to medication errors in the intensive care unit. A large proportion (87.6%) of doses for weight-based infusions was calculated based on estimated or unreliable admission weights. There were no severe consequences resulting from the errors observed in this 1 month investigation; however, depending on the pharmacokinetic characteristics of the drug being administered, there is a potential to deliver artificially low or high doses resulting in subtherapeutic or adverse effects.
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Medication Errors and Adverse Drug Events in Pediatric Inpatients
Rainu Kaushal · JAMA · 2001 · 1.9K citations