Lipophilicity of antibacterial fluoroquinolones

Substituent Constants for Correlation Analysis in Chemistry and Biology.

Gordon L. Flynn · Journal of Pharmaceutical Sciences · 1980 · 2.8K citations

Pharmacy, Chemistry, Medicinal Chemistry +12

The fluoroquinolones: structures, mechanisms of action and resistance, and spectra of activity in vitro

J S Wolfson, David C. Hooper · Antimicrobial Agents and Chemotherapy · 1985 · 700 citations

Medicine, Medicinal Chemistry, Pharmacology +6

Structure-activity relationships of antibacterial 6,7- and 7,8-disubstituted 1-alkyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids

Hiroshi Koga, Akira Itoh, Satoshi Murayama et al. · Journal of Medicinal Chemistry · 1980 · 483 citations

Pharmacy, Chemistry, Medicinal Chemistry +13

Aqueous solubilities of some variously substituted quinolone antimicrobials

Danna L. Ross, Christopher M. Riley · International Journal of Pharmaceutics · 1990 · 292 citations

Pharmacy, Medicinal Chemistry, Pharmaceutical Analysis +5

Differences in susceptibility to quinolones of outer membrane mutants of Salmonella typhimurium and Escherichia coli

Keiji Hirai, Hiroshi Aoyama, Tsutomu Irikura et al. · Antimicrobial Agents and Chemotherapy · 1986 · 254 citations

Natural Sciences, Biophysics, Microbiology +17