Contrasting Actions of Philanthotoxin-343 and Philanthotoxin-(12) on Human Muscle Nicotinic Acetylcholine Receptors

Ionic Blockage of Sodium Channels in Nerve

Ann M. Woodhull · The Journal of General Physiology · 1973 · 1.6K citations · Full text

Sodium Permeability, Anesthetic Mechanism, Peripheral Nervous System +19

Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazine.

J. Giraudat, Michael Dennis, Thiérry Heidmann et al. · Proceedings of the National Academy of Sciences · 1986 · 300 citations · Full text

Proteinlipid Interaction, Protein Secretion, Neurotransmitter +17

An open-channel blocker interacts with adjacent turns of α-helices in the nicotinic acetylcholine receptor

Pierre Charnet, Cesar Labarca, Reid J. Leonard et al. · Neuron · 1990 · 283 citations

Molecular Pharmacology, Molecular Physiology, Signal Transduction +13

Structure and synthesis of a potent glutamate receptor antagonist in wasp venom.

Amira T. Eldefrawi, Mohyee E. Eldefrawi, Katsuhiro Konno et al. · Proceedings of the National Academy of Sciences · 1988 · 204 citations

Molecular Pharmacology, Biochemistry, Medicine +14

The human medulloblastoma cell line TE671 expresses a muscle‐like acetylcholine receptor Cloning of the α‐subunit cDNA

Ralf Schoepfer, Michael Luther, Jon Lindstrom · FEBS Letters · 1988 · 111 citations

Molecular Biology, Synaptic Signaling, Cellular Physiology +22