Concepedia

Biochemical basis of the prevention of 6-thiopurine toxicity by the nucleobases, hypoxanthine and adenine

Hisako Hashimoto, Masaru Kubota, Tsunehiro Shimizu, Tetsuya Takimoto, Toshiyuki Kitoh, Yuichi Akiyama, Harukí Mikawa

Leukemia Research · 1990 · 10 citations · 18 references

DOI

Concepts

References

18

Clinical Evaluation of a New Antimetabolite, 6-Mercaptopurine, in the Treatment of Leukemia and Allied Diseases

Joseph H. Burchenal, M. Lois Murphy, Rose Ruth Ellison et al. · Blood · 1953 · 391 citations · Full text

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A biochemical mechanism for the delayed cytotoxic reaction of 6-mercaptopurine.

D M Tidd, Alan R. P. Paterson · PubMed · 1974 · 282 citations

, , +9

Adenosine phosphorylase-mediated nucleoside toxicity

Gerard J. McGarrity, Dennis A. Carson · Experimental Cell Research · 1982 · 95 citations

, , +10

Purine and pyrimidine transport and phosphoribosylation and their interaction in overall uptake by cultured mammalian cells. A re-evaluation

Richard März, Robert M. Wohlhueter, Peter G.W. Plagemann · Journal of Biological Chemistry · 1979 · 86 citations · Full text

, , +16

Distinction between inhibition of purine nucleotide synthesis and the delayed cytotoxic reaction of 6-mercaptopurine.

D M Tidd, Alan R. P. Paterson · PubMed · 1974 · 79 citations

, , +11