Effects of loratadine on cytosolic Ca2+ levels and leukotriene release: novel mechanisms of action independent of the anti-histamine activity

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.

André DeLÉAN, Peter J. Munson, David Rodbard · American Journal of Physiology-Endocrinology and Metabolism · 1978 · 2.4K citations

Medicine, Biostatistics, Pharmacology +17

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

Roger Y. Tsien, Tullio Pozzan, T J Rink · The Journal of Cell Biology · 1982 · 2.3K citations · Full text

Life Sciences, Biochemistry, Biophysics +13

Activation of Calcium Entry by the Tumor Promoter Thapsigargin in Parotid Acinar Cells

Haruo Takemura, Arlene R. Hughes, Ole Thastrup et al. · Journal of Biological Chemistry · 1989 · 886 citations · Full text

Life Sciences, Cell Biology, Pharmacology +14

Enzyme immunoassays of eicosanoids using acetylcholine esterase as label: an alternative to radioimmunoassay

P. Pradelles, Jacques Grassi, Jacques Maclouf · Analytical Chemistry · 1985 · 704 citations

Life Sciences, Pharmacology, Analytical Toxicology +10