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Study of FTMT and ABCA4 genes in a patient affected by age-related macular degeneration: identification and analysis of new mutations

DOI

20

Citations

0

References

2012

Year

Stefania Stenirri, Paolo Santambrogio, Marco Setaccioli, Benedetta Gaia Erba, Maria Pia Manitto, Ermanna Rovida, Maurizio Ferrari, Sonia Levi, Laura Cremonesi
Clinical Chemistry and Laboratory Medicine (CCLM)

Abstract

Our findings suggest that the FtMt mutation may determine a condition similar to haploinsufficiency resulting in a reduced protection from iron-dependent oxidative stress in mitochondria.