Journal Of Clinical Periodontology · 1988 · 38 citations · 10 references
DentistryDental HygieneOral PathologyHistopathologyOral DiagnosisOral HistopathologyBiopsy Of Oral LesionsOral ConditionsDiagnostic HistopathologyOral Lesion Differential DiagnosisOral Mucosal HistopathologyOral Tetracycline TherapyPediatric Oral PathologyPeriodontitis Diagnosis
A case of prepubertal periodontitis in a 6 1/2-year-old boy is described. Following failure to respond to conventional treatment including scaling, oral hygiene instruction and tetracycline therapy, a biopsy was performed and root planing carried out. The biopsy revealed histiocytic infiltration and a diagnosis of Histiocytosis X of the Hand-Schüller-Christian type was made. This case emphasises the role of biopsy in establishing a diagnosis in cases of prepubertal periodontitis that do not respond to conventional therapy.
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Michael E. Osband, Jeffrey M. Lipton, Philip T. Lavin et al. · New England Journal of Medicine · 1981 · 223 citations
Life Sciences, Immunology, Pathology +16