Psychopathology · 2010 · 25 citations · 0 references
MedicineNeurosciencePsychiatryEye MovementsNeuropharmacologyPsychopharmacologyEye Movement DisordersEye-movement ControlOcular MotilitySchizophrenia PharmacotherapySchizophrenia Spectrum DisordersSmooth PursuitClinical Assessment Of PursuitPursuit Eye Movement AssessmentPursuit Eye Movement DisordersSmooth Pursuit AbnormalitiesSmooth Pursuit AnalysisSmooth Pursuit DeficitsSmooth Pursuit Eye Movement Physiology
The authors investigated smooth pursuit eye movements (SPEMs) in 66 schizophrenic and 40 major affective patients and 39 healthy controls. The results showed significant differences of both patient groups as compared to the controls. Schizophrenics with neuroleptic treatment in the preceding 2 years were significantly more disturbed than the controls, the affective patients and the untreated schizophrenics. Acute neuroleptic medication and neuroleptic treatment of a duration of 4-6 weeks appear not to significantly influence the quality of SPEMs.