Antimicrobial Agents and Chemotherapy · 1977 · 59 citations · 10 references
Life SciencesBiochemistryMicrobiologyAntimicrobial ResistanceEnzymologyMedical MicrobiologyAntibacterial ResistanceAntibiotic ResistanceAntibiotic Resistance MechanismsMechanisms Of Antimicrobial ResistancePlasmid BiologyPlasmid GeneticsAminoglycoside Resistance PlasmidsAminoglycoside-modifying EnzymesAntibiotic Resistance PlasmidsEnzyme-mediated Antibiotic Resistance MechanismsPlasmid Transfer SystemsPlasmid-borne Antibiotic ResistanceResistance In Clinical IsolatesResistance Mechanisms In Staphylococci
A plasmid-mediated aminoglycoside phosphotransferase that phosphorylates amikacin has been detected in clinical isolates of Staphylococcus aureus. This enzyme does not confer detectable amikacin resistance to the strains.
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