Plasmid-Mediated Aminoglycoside Phosphotransferase of Broad Substrate Range That Phosphorylates Amikacin

Abstract

A plasmid-mediated aminoglycoside phosphotransferase that phosphorylates amikacin has been detected in clinical isolates of Staphylococcus aureus. This enzyme does not confer detectable amikacin resistance to the strains.