Publication | Closed Access
On the origins of drug polypharmacology
140
Citations
78
References
2012
Year
Multiple ProteinsMedicinal ChemistryDrug PolypharmacologyMany DrugsDrug TargetBiochemistryDrug DesignNatural SciencesMedicineRational Drug DesignEarly Protein EvolutionDrug DevelopmentChemical BiologyPharmacologyDrug ClassDrug DiscoveryPharmaceutical Research
The ability of many drugs, unintended most often, to interact with multiple proteins is commonly referred to as polypharmacology. Could this be a reminiscent chemical signature of early protein evolution?
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