Journal of Materials Chemistry · 2012 · 224 citations · 30 references
MedicineBiomedical EngineeringBiomedical SciencesBiomedical ImagingDiagnostic ImagingMolecular ImagingCarbon NanomaterialsFluorescence ImagingInorganic NanoparticlesMagnetic Resonance ImagingNanomedicineTheranostic NanoparticlesBiomedical ApplicationsCarbon DotsFluorescence Imaging ProbesFluorescence ProbesFluorescent ProbesNanoparticle-based ProbesT1 ContrastT1-weighted Imaging
We describe the synthesis of Gd(III)-doped carbon dots as dual fluorescence-MRI probes for biomedical applications. The derived Gd(III)-doped carbon dots show uniform particle size (3–4 nm) and gadolinium distribution and form stable dispersions in water. More importantly, they exhibit bright fluorescence, strong T1-weighted MRI contrast and low cytotoxicity.
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