Cloning of WWOX gene and its growth-inhibiting effects on ovarian cancer cells

WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer.

Andrzej K. Bednarek, K J Laflin, Rachael Daniel et al. · PubMed · 2000 · 428 citations

Life Sciences, Genetics, Molecular Genetics +10

WWOX, the FRA16D gene, behaves as a suppressor of tumor growth.

Andrzej K. Bednarek, C.L. Keck-Waggoner, Rachael Daniel et al. · PubMed · 2001 · 277 citations

Life Sciences, Genetics, Oncology +14

Functional association between Wwox tumor suppressor protein and p73, a p53 homolog

Rami I. Aqeilan, Yuri Pekarsky, Juan J. Herrero et al. · Proceedings of the National Academy of Sciences · 2004 · 235 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

<i>WWOX</i> : A candidate tumor suppressor gene involved in multiple tumor types

Adam J.W. Paige, Karen J. Taylor, Claire Taylor et al. · Proceedings of the National Academy of Sciences · 2001 · 218 citations · Full text

Medicine, Genetics, Molecular Genetics +14

WWOX protein expression varies among ovarian carcinoma histotypes and correlates with less favorable outcome

Maria I. Nuñez, Daniel Rosen, John Ludes-Meyers et al. · BMC Cancer · 2005 · 98 citations · Full text

Medicine, Oncology, Pathology +17