Targeted gene deletion of the 5-HT3A receptor subunit produces an anxiolytic phenotype in mice

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

Sharon Pellow, Philippe Chopin, Sandra E. File et al. · Journal of Neuroscience Methods · 1985 · 5.8K citations

Social Sciences, Behavioral Sciences, Psychology +9

Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: A novel test of anxiety in the rat

Sharon Pellow, Sandra E. File · Pharmacology Biochemistry and Behavior · 1986 · 1.5K citations

Medicine, Neuroscience, Pharmacology +13

Primary Structure And Functional Expression of the 5HT ₃ Receptor, A Serotonin-gated Ion Channel

Andres V. Maricq, Andrew S. Peterson, Anthony J. Brake et al. · Science · 1991 · 983 citations

Life Sciences, Neuroscience, Pharmacology +17

5-HT3 receptors are membrane ion channels

V. A. Derkach, Annmarie Surprenant, R A North · Nature · 1989 · 629 citations

Medicine, Pharmacology, Physiology +14

The 5-HT3B subunit is a major determinant of serotonin-receptor function

Paul Davies, Marco Pistis, Michael C. Hanna et al. · Nature · 1999 · 562 citations

Life Sciences, Neuroscience, Pharmacology +16