Circadian Periodicity of Bone Marrow Mitotic Activity and Reticulocyte Counts in Rats and Mice

Ray H. Clark, Donald R. Korst

Science · 1969 · 50 citations · 10 references

Concepts

Abstract

Mitotic proliferation in the bone marrow of female rats and mice kept under standardized coniditions with light from 6:00 a.m. to 6:00 p.m. exhibited a significant circadian periodicity with the greatest activity occurring from 6:00 a.m. to 12:00 noon. The reticulocyte levels in peripheral blood were highest at 8:00 a.m.

References

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