Upregulation of Toll-like receptor (TLR) expression and release of cytokines from P815 mast cells by GM-CSF

Abstract

The ability of GM-CSF in modulation of expression of TLR3 and TLR7 in P815 mast cells and in stimulation of IL-13 and IL-6 release from P815 mast cells in vitro suggests that GM-CSF might play an important role in enhancing the innate immune responses of mast cell to viral infection.