Effect of amperozide on rat cortical 5-HT2 and striatal and limbic dopamine D2 receptor occupancy: Implications for antipsychotic action

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

Ian Creese, David R. Burt, Solomon H. Snyder · Science · 1976 · 2.2K citations

Medicine, Neuroscience, Pharmacology +14

Effect of Chlorpromazine or Haloperidol on Formation of 3‐Methoxytyramine and Normetanephrine in Mouse Brain

Arvid Carlsson, Margit Lindqvist · Acta Pharmacologica et Toxicologica · 1963 · 2.1K citations

Medicine, Neuroscience, Pharmacology +9

Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values.

Herbert Y. Meltzer, Shin Matsubara, J C Lee · Journal of Pharmacology and Experimental Therapeutics · 1989 · 1.4K citations

Medicine, Pharmacology, Psychiatry +17

Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: Radioligand binding studies with [3H]5-HT, [3H]8-OH-DPAT, (−)[125I]iodocyanopindolol, [3H]mesulergine and [3H]Ketanserin

Daniël Hoyer, G. Engel, Hans O. Kalkman · European Journal of Pharmacology · 1985 · 577 citations

Life Sciences, Neuroscience, Pharmacology +13

Receptor-binding properties in vitro and in vivo of ritanserin: A very potent and long acting serotonin-S2 antagonist.

J.E. Leysen, W Gommeren, Paul Van Gompel et al. · Molecular Pharmacology · 1985 · 453 citations

Medicine, Medicinal Chemistry, Pharmacology +13