LINE-1 ORF-1p functions as a novel androgen receptor co-activator and promotes the growth of human prostatic carcinoma cells

The Human LINE-1 Retrotransposon Creates DNA Double-strand Breaks

Stephen L. Gasior, Timothy P. Wakeman, Bo Xu et al. · Journal of Molecular Biology · 2006 · 522 citations · Full text

Life Sciences, Genetics, Molecular Genetics +8

Transcriptional disruption by the L1 retrotransposon and implications for mammalian transcriptomes

Jeffrey S. Han, Suzanne Szak, Jef D. Boeke · Nature · 2004 · 494 citations

Life Sciences, Genetics, Molecular Genetics +15

A Cohort Study of Tumoral LINE-1 Hypomethylation and Prognosis in Colon Cancer

Shuji Ogino, Katsuhiko Nosho, Gregory J. Kirkner et al. · JNCI Journal of the National Cancer Institute · 2008 · 376 citations · Full text

Medicine, Genetics, Oncology +17

Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia

José Román‐Gómez, Antonio Jiménez‐Velasco, Xabier Agirre et al. · Oncogene · 2005 · 214 citations · Full text

Medicine, Genetics, Molecular Biology +14

Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway

Chang Xia, Jing Fang, Yon Rojanasakul et al. · Cellular Signalling · 2006 · 213 citations

Medicine, Molecular Biology, Oncology +16