Allopurinol-induced toxic pustuloderma

Abstract

We report the case of a 67-year-old man who developed a pustular eruption, fever, neutrophilia and eosinophilia, following a short course of allopurinol. Toxic pustuloderma is an uncommon form of generalized pustular eruption with several characteristic clinical and pathological features. A number of drugs have been incriminated, but to our knowledge this is the first reported case of toxic pustuloderma occurring after the administration of allopurinol.