Journal of Clinical Psychopharmacology · 1988 · 21 citations · 0 references
PharmacyPharmacotherapyPsychiatryNeuropharmacologyPsychiatric PharmacotherapyPsychopharmacologyAntidepressant PharmacotherapyAntidepressant TherapyAnxiety Disorder PharmacotherapyAnxiety DisordersAnxiolytic PharmacotherapyPanic DisorderAdult Anxiety DisordersAgoraphobia TreatmentPanic Disorder TreatmentPanic EpisodesSerotonin-norepinephrine Reuptake Inhibitor TreatmentSerotonin-norepinephrine Reuptake Inhibitor UseTreatment Of Anxiety DisordersTreatment Outcome Analysis
Thirty-four consecutive patients with panic disorder or agoraphobia with panic attacks were treated with nortriptyline at the LAC-USC Medical Center's Anxiety Disorders Clinic. Fourteen (67%) of the 21 completers totally lost their panic attacks, five (24%) showed partial improvement, and two (10%) showed no improvement. The relationship of treatment outcome to pretreatment and posttreatment measures of depression is discussed, in addition to the potential role of nortriptyline in treating panic attacks in clinical practice.