Selective and segmentally restricted antinociception induced by MPV‐2426, a novel alpha‐2‐adrenoceptor agonist, following intrathecal administration in the rat

Abstract

MPV-2426 produces a selective and segmentally more restricted antinociceptive effect than dexmedetomidine following i.t. administration. The antinoception induced by MPV-2426 is due to action on spinal alpha-2-adrenoceptors.