Self‐Assembled Synthetic Viral Capsids from a 24‐mer Viral Peptide Fragment

Abstract

Assemble a virus: A chemical strategy to de novo design “tailor-made” viruslike nanocapsules was developed (see picture). 24-mer β-annulus peptides of the tomato bushy stunt virus (TBSV) spontaneously self-assemble into hollow nanocapsules with a size of 30–50 nm. The hollow structure of the assemblies was clearly revealed by small-angle X-ray scattering (SAXS). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.