Upregulation of Pentraxin-3 in Human Endothelial Cells After Lysophosphatidic Acid Exposure

Abstract

Our findings favor the proatherogenic role of LPA, a bioactive lipid produced by activated platelets and present in oxLDL, because it enhances pentraxin-3 secretion that could contribute to the accumulation of monocytes in the atherosclerotic lesion.