<scp>IL</scp>‐13‐induced<scp>MUC5AC</scp>production and goblet cell differentiation is steroid resistant in human airway cells

Abstract

Dex at therapeutic concentrations did not inhibit the effects of IL-13 on goblet cell differentiation, characteristic of severe asthma. Paradoxically, MUC5AC production was increased with lower dose IL-13 exposure. This may lead to airway mucus obstruction commonly seen in life-threatening asthma.