Complementary addressed modification of double‐stranded DNA within a ternary complex

Olga S. Fedorova, D.G. Knorre, Larisa M. Podust

FEBS Letters · 1988 · 42 citations · 7 references

Concepts

Abstract

Double-stranded DNA containing a d(pG)18.d(pC)18 sequence was shown to be selectively alkylated in the vicinity of this fragment using the 5'-p-(N-2-chloroethyl-N-methylamino)benzylamide of deoxyribooligocytidylate, CIRCH2NH(pdC)n (n = 9,15), in conditions favouring triple-stranded complex formation.

References

7